| CAS No.: | Hyaluronic Acid Sodium Powder |
|---|---|
| Formula: | Hyaluronic Acid Sodium Powder |
| EINECS: | Hyaluronic Acid Sodium Powder |
| Type: | Pharmaceutical Intermediates |
| Appearance: | Powder |
| Quality: | Technical |
| Samples: |
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| Customization: |
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| Items | Specifications |
| Appearance | White to pale yellow powder or granule |
| Identification A. Infrared absorption B. Reaction of sodium |
Complies with the Ph.Eur. reference spectrum of Sodium Hyaluronate Positive |
| H | 6.0 ~ 8.0 (0. 1% solution) |
| Light transmittance | ≥ 99.0% (0.5% solution) |
| Intrinsic viscosity | 1.72 m3/kg ~ 2.90 m3/kg |
| Molecular Weight | 1.0 x 106 Da ~ 1.8 x 106 Da |
| Protein | The absorbance is NMT 0.5 at 280 nm |
| ≤ 0.3% (on the dried substance) | |
| Loss on drying | ≤ 10.0% |
| Ash | ≤ 13.0% |
| Residue on ignition | ≤ 20.0% (on the dried substance) |
| Heavy metals | ≤ 20 ppm |
| Arse | ≤ 2 ppm |
| Assay | ≥ 95.0% (on the dried substance) |
| Total aerobic microbial count | ≤100 cfu/g |
| Total combined yeasts/mould count | ≤ 10 cfu/g |
| Escherichia Coli | Absent/g |
| Salmonella | Absent/10 g |
| Staphylococcus aureus | Absent/g |
| Pseudomonas aeruginosa | Absent/g |
1. Hydrates Dry, Aged Skin
Hyaluronic Acid Serum is a hydrator. Many people report that their skin feels "dewier," the bags under their eyes become lighter and their skin texture is smoother after applying serums containing hyaluronic acid. Hyaluronic acid can help naturally reduce signs of aging by decreasing "epidermis water loss" associated with sun exposure, skin dryness or flakiness.
2. Helps Reduce Wrinkles
Although most research shows that hyaluronic acid might take six weeks or more to improve skin's appearance, some studies have found that anti-wrinkle hyaluronic acid serums and eye creams can sometimes start to work within just two to four weeks of use.
3. Sores, Sunburn and Wound Repair
Aside from lowering the appearance of wrinkles and dryness, hyaluronic acid is beneficial for treating cold sores and mouth sores, ulcers, wounds, bites and burns due to how hyaluronic acid keeps damaged tissue moist. Tissue repair benefits also include sunburn relief. Many cold sore treatments for the lips and mouth contain hyaluronic acid gel to speed up the healing process and prevent cracking or bleeding.
4. Lubricates Achy Joints
Hyaluronic Acid Serum is now a popular substance used in supplements for treating osteoarthritis pain and injuries. Hyaluronic acid has also been approved for treatment of osteoarthritis when administered in relatively high doses through injections given by a health care provider.
5. Helps Reduce Dry Eyes and Eye Discomfort
The fluid inside the eye socket (called the vitreous humor) is composed almost completely of hyaluronic acid. Hyaluronic acid eye drops (such as the brand Hyalistil) can help relieve chronic dry eyes by replenishing moisture within the eye socket, helping with tear production and restoring fluid balance. Some studies have also found that hyaluronic acid helps suppress oxidative damage caused by UVB light within the cornea.
Sodium hyaluronate is an anionic unsulfidized glycosaminoglycan widely distributed in connective tissue, epithelial tissue and nerve tissue.Sodium hyaluronate can be extracted from the comb or fermented by lactic acid coccus. It is white or similar white granules or powders without odor. When dried, the nitrogen content is 2.8%-4.0%, and the glucuronic acid content is 37.0%-51.0%.Use more in cosmetic domain, have protect wet effect.
Application
1. Food Industry
We recommand Food Grade with the Molecular Weight 800,000Da-1,200,000Da. It can be added into drinks, mink products, health care capsules, etc.
2. Cosmetic Industry
(1) <10,000Da (Super Low Molecular Weight):
Making hyaluronic acid smaller means it can reach a bit farther into skin's uppermost layers for visibly enhanced results, so it has the best effect of moisturzing and anti-aging.
(2) 10,000Da-200,000Da (Low Molecular Weight)
It has better moisture effect than regular molecular weight.
(3) 200,000Da-1,600,000Da (Regular Molecular Weight)
It can retain moisture, keep the skin firm, and prevent wrinkles by adding volume to the skin.
(4) >1,600,000Da (High Molecular Weight)
It can keep moisturing for longer time, and repair skins.
3. Eyedrop Industry
We recommand Eyedrop Grade for you. It can be used in eye surgeries including cataract removal, corneal transplantation, and repair of a detached retina and other eye injuries.
4. Injection Industry
We recommand Injection Grade for you. It can be made into HA filler used on our body, like face, lip, breast, etc.
Specification
| Items | Specifications |
| Characters | White or almost white powder |
| Glucuronic acid | ≥44.5% |
| Sodium hyaluronate | ≥92.0% |
| Ph(0.5% aq,sol.,25ºC) | 5.0-8.5 |
| Absorbance (0.5%, aq.sol.25ºC) | A280nm≤0.25 |
| Appearance of solution (0.5% aq.sol.25ºC) | T550nm≥99.0% |
| Loss on drying | ≤10.0% |
| Molecular weight | ≥2,000,000 |
| Intrinsic viscosity | Measured value |
| Kinematic viscosity | Measured value |
| Protein | ≤0.1% |
| Heavy metal (as pb) | ≤20ppm |
| Bacteria counts | ≤100cfu/g |
| Mold & yeast | ≤50cfu/g |
| Staphylococcus aureus | Negative |
| Pseudomonas aeruginosa | Negative |
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